Assay Detail
Functional
CHEMBL709128
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Compound was evaluated for cytotoxicity against breast cancer MCF-7 cell lines
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New aza-thioxanthones: Synthesis and cytotoxicity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.67 | 4.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL354332 | — | — | 1 | 4.88 |
| CHEMBL355131 | — | — | 1 | 4.80 |
| CHEMBL355207 | — | — | 1 | 4.77 |
| CHEMBL171167 | — | — | 1 | 4.71 |
| CHEMBL355342 | — | — | 1 | 4.57 |
| CHEMBL172744 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL354332 | — | IC50 | = | 13300.0 | nM | 4.88 |
| CHEMBL355131 | — | IC50 | = | 15900.0 | nM | 4.80 |
| CHEMBL355207 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL171167 | — | IC50 | = | 19400.0 | nM | 4.71 |
| CHEMBL355342 | — | IC50 | = | 27200.0 | nM | 4.57 |
| CHEMBL172744 | — | IC50 | = | 49800.0 | nM | 4.30 |