Assay Detail
Functional
CHEMBL709467
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Cytotoxicity against MOLT-4 human leukemic lymphoblastoid cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
2'-O-nitro-1-beta-D-arabinofuranosylcytosine. A new derivative of 1-beta-D-arabinofuranosylcytosine that resists enzymatic deamination and has antileukemic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.20 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 8.00 |
| CHEMBL3142688 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL3142688 | — | IC50 | = | 400.0 | nM | 6.40 |