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Assay Detail

CHEMBL709528

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Binding
In vitro inhibitory activity against matrix metalloprotease-3
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Stromelysin-1 (CHEMBL283)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases.
Pikul S, Ohler NE, Ciszewski G, Laufersweiler MC, Almstead NG, De B, Natchus MG, Hsieh LC, Janusz MJ, Peng SX, Branch TM, King SL, Taiwo YO, Mieling GE.
J Med Chem (2001) 44 : 2499 -2502
PubMed 11472202 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.32 5.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL79906 1 5.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL79906 IC50 = 4840.0 nM 5.32