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Assay Detail

CHEMBL709765

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibitory binding activity towards metabotropic glutamate receptor (mGluRla) expressed in LLC-PK1 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type LLC-PK1
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 1 (CHEMBL3772)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis of conformationally-constrained stereospecific analogs of glutamic acid as antagonists of metabotropic receptors
Tellier F, Acher F, Brabet I, Pin J, Bockaert J, Azerad R
Bioorg Med Chem Lett (1995) 5 : 2627 -2632
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.03 5.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL39215 1 5.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL39215 EC50 = 9300.0 nM 5.03