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Assay Detail

CHEMBL710413

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested in vitro for cytotoxic activity against MCF-7 cell line (human breast carcinoma)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Intermediate

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

An exceptionally potent analog of sandramycin
Boger DL, Chen J
Bioorg Med Chem Lett (1997) 7 : 919 -922
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.46 10.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL265841 1 10.40
CHEMBL441158 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL265841 IC50 = 0.04 nM 10.40
CHEMBL441158 IC50 = 300.0 nM 6.52