Assay Detail
Functional
CHEMBL710652
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In vitro inhibitory activity against LL murine NSCLC cell line;
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Lewis lung carcinoma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.31 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL168402 | — | — | 1 | 5.73 |
| CHEMBL169978 | — | — | 1 | 5.54 |
| CHEMBL39594 | — | — | 1 | 5.53 |
| CHEMBL166973 | — | — | 1 | 5.46 |
| CHEMBL168696 | — | — | 1 | 4.98 |
| CHEMBL167099 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL168402 | — | IC50 | = | 1870.0 | nM | 5.73 |
| CHEMBL169978 | — | IC50 | = | 2860.0 | nM | 5.54 |
| CHEMBL39594 | — | IC50 | = | 2930.0 | nM | 5.53 |
| CHEMBL166973 | — | IC50 | = | 3470.0 | nM | 5.46 |
| CHEMBL168696 | — | IC50 | = | 10550.0 | nM | 4.98 |
| CHEMBL167099 | — | IC50 | = | 24180.0 | nM | 4.62 |