Assay Detail
Functional
CHEMBL710919
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Evaluated for the inhibitory concentration required to cause growth inhibition of MCF-7ADR breast cell line using the MTT Cytotoxicity Assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI/ADR-RES |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1,3-Dialkyl-3-acyltriazenes, a novel class of antineoplastic alkylating agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.56 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87938 | — | — | 1 | 4.77 |
| CHEMBL85702 | — | — | 1 | 4.64 |
| CHEMBL87240 | — | — | 1 | 4.62 |
| CHEMBL84852 | — | — | 1 | 4.47 |
| CHEMBL86892 | — | — | 1 | 4.46 |
| CHEMBL316041 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87938 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL85702 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL87240 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL84852 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL86892 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL316041 | — | IC50 | = | 40000.0 | nM | 4.40 |