Assay Detail
Binding
CHEMBL711027
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested to inhibit lipoprotein lipase (LPL)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339297 | — | — | 1 | 6.70 |
| CHEMBL133897 | — | — | 1 | - |
| CHEMBL131588 | — | — | 1 | - |
| CHEMBL131051 | — | — | 1 | - |
| CHEMBL106126 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339297 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL133897 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL131588 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL131051 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL106126 | — | IC50 | > | 50000.0 | nM | - |