Assay Detail
Binding
CHEMBL711157
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for its activity at group I mGluRs for the generation of [3H]inositol phosphate using [3H]inositol pre-labelled guinea-pig cerebral cortex slices.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Cerebral cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
DHPMP: a novel group I specific metabotropic glutamate receptor agonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.73 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39221 | — | — | 1 | 4.90 |
| CHEMBL67275 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39221 | — | EC50 | = | 12589.25 | nM | 4.90 |
| CHEMBL67275 | — | EC50 | = | 27542.29 | nM | 4.56 |