Assay Detail
Functional
CHEMBL711489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against rhinoviral-19 serotype in a plaque inhibition assay using monolayers of M-HeLa cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human rhinovirus sp. |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and antirhinovirus activity of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.11 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL299013 | — | — | 1 | 5.27 |
| CHEMBL283830 | — | — | 1 | 5.17 |
| CHEMBL48774 | — | — | 1 | 5.11 |
| CHEMBL298184 | — | — | 1 | 5.07 |
| CHEMBL299993 | — | — | 1 | 5.05 |
| CHEMBL49668 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL299013 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL283830 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL48774 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL298184 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL299993 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL49668 | — | IC50 | = | 10000.0 | nM | 5.00 |