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Assay Detail

CHEMBL711548

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human matrix metalloprotease-7 (MMP-7)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Matrilysin (CHEMBL4073)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers.
Fray MJ, Dickinson RP, Huggins JP, Occleston NL.
J Med Chem (2003) 46 : 3514 -3525
PubMed 12877590 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45483 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45483 IC50 = 30.0 nM 7.52