Assay Detail
Binding
CHEMBL711552
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Inhibition of human matrix metalloprotease 7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.25 | 6.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL514138 | CGS-27023A | — | 1 | 6.97 |
| CHEMBL176602 | — | — | 1 | 6.05 |
| CHEMBL355752 | — | — | 1 | 5.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL514138 | CGS-27023A | IC50 | = | 106.0 | nM | 6.97 |
| CHEMBL176602 | — | IC50 | = | 886.0 | nM | 6.05 |
| CHEMBL355752 | — | IC50 | = | 1860.0 | nM | 5.73 |