Assay Detail
Binding
CHEMBL711557
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Inhibition of Matrix metalloprotease-7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Heterocycle-based MMP inhibitors with P2' substituents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.91 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267939 | — | — | 1 | 6.13 |
| CHEMBL427616 | — | — | 1 | 6.04 |
| CHEMBL268114 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267939 | — | IC50 | = | 737.0 | nM | 6.13 |
| CHEMBL427616 | — | IC50 | = | 905.0 | nM | 6.04 |
| CHEMBL268114 | — | IC50 | = | 2780.0 | nM | 5.56 |