Assay Detail
Functional
CHEMBL711580
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Inhibitory concentration for anti-HCMV activity against AD-169 strain in MRC-5 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiviral oligo- and polyribonucleotides containing selected triazolo[2,3-a]purines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.89 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3144270 | — | — | 1 | 6.82 |
| CHEMBL3144269 | — | — | 1 | 6.37 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.20 |
| CHEMBL3144268 | — | — | 1 | 5.17 |
| CHEMBL3144271 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3144270 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL3144269 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL182 | GANCICLOVIR | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL3144268 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL3144271 | — | IC50 | > | 2800.0 | nM | - |