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Assay Detail

CHEMBL711762

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration that provides 50% protection in the MO/Mphi cells infected with HIV-1 Ba-L strain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type MO/Mphi
Confidence 1 — Organism
Curated By Intermediate

Target

MO/Mphi (CHEMBL614174)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of an alkenyldiarylmethane (ADAM) which acts as a novel non-nucleoside HIV-1 reverse transcriptase inhibitor
Cushman M, Golebiewski M, Buckheit RW, Graham L, Rice WG
Bioorg Med Chem Lett (1995) 5 : 2713 -2716
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.26 5.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL58542 1 5.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL58542 EC50 = 5500.0 nM 5.26