Assay Detail
Functional
CHEMBL712105
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Inhibitory concentration of compound against growth of human breast carcinoma cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.02 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108063 | — | — | 1 | 7.40 |
| CHEMBL106653 | — | — | 1 | 7.22 |
| CHEMBL108793 | — | — | 1 | 7.05 |
| CHEMBL280643 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108063 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL106653 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL108793 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL280643 | — | IC50 | = | 400.0 | nM | 6.40 |