Assay Detail
Functional
CHEMBL712309
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibitory concentration of compound was measured against human gastric adenocarcinoma cell line (MKN-1)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MKN-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Preparation of 5-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyloxy)-6-hydroxynap htho[2,3- f]quinoline-7,12-dione (FT-Alz), a new-type, potentially antitumor substance with various biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.73 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.19 |
| CHEMBL64993 | — | — | 1 | 6.14 |
| CHEMBL65716 | — | — | 1 | 4.85 |
| CHEMBL405065 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL64993 | — | IC50 | = | 730.0 | nM | 6.14 |
| CHEMBL65716 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL405065 | — | IC50 | > | 8500.0 | nM | - |