Assay Detail
Binding
CHEMBL713682
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Inhibition of horseradish peroxidase by spectrophotometric method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Armoracia rusticana |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.61 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | 3.0 | 1 | 4.77 |
| CHEMBL374863 | EBSELEN DITELLURIDE | — | 1 | 4.76 |
| CHEMBL385817 | EBSELEN DISELENIDE | — | 1 | 4.30 |
| CHEMBL376704 | — | — | 1 | - |
| CHEMBL220461 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | IC50 | = | 16900.0 | nM | 4.77 |
| CHEMBL374863 | EBSELEN DITELLURIDE | IC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL385817 | EBSELEN DISELENIDE | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL376704 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL220461 | — | IC50 | > | 100000.0 | nM | - |