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Assay Detail

CHEMBL713829

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the inhibition of Manca human lymphoma cell growth
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Manca
Confidence 1 — Organism
Curated By Intermediate

Target

Manca (CHEMBL614320)
Type CELL-LINE
Organism Homo sapiens

Publication

5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities.
Gangjee A, Patel J, Kisliuk RL, Gaumont Y.
J Med Chem (1992) 35 : 3678 -3685
PubMed 1433179 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.38 4.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL331208 1 4.38
CHEMBL122959 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL331208 IC50 = 42000.0 nM 4.38
CHEMBL122959 IC50 > 10000.0 nM -