Assay Detail
Functional
CHEMBL714241
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Steady-State [Ca2+] Release from Saponin-Permeabilized Lvec Cell Lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Lvec |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, calcium mobilizing, and physicochemical properties of D-chiro-inositol 1,3,4,6-tetrakisphosphate, a novel and potent ligand at the D-myo-inositol 1,4,5-trisphosphate receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.33 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | — | 1 | 6.61 |
| CHEMBL1160286 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | EC50 | = | 247.0 | nM | 6.61 |
| CHEMBL1160286 | — | EC50 | = | 906.0 | nM | 6.04 |