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Assay Detail

CHEMBL715088

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against NCI tumor panel, MCF-7 breast cancer cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Intermediate

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and preliminary biological evaluations of CC-1065 analogues: effects of different linkers and terminal amides on biological activity.
Wang Y, Yuan H, Ye W, Wright SC, Wang H, Larrick JW.
J Med Chem (2000) 43 : 1541 -1549
PubMed 10780911 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.32 9.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38957 1 9.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38957 IC50 = 0.476 nM 9.32