Assay Detail

CHEMBL715131

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

In vitro cytotoxic activity against human breast (MCF-7) cell line

ChEMBL ↗

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Target

MCF7 (CHEMBL387) ↗

Open DB target context

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Primary target MCF7

CHEMBL387

Anchored from Assay target.

Protein identity MCF7

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MCF7
Confidence	1 — Organism
Curated By	Intermediate

Target

MCF7 (CHEMBL387) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Structural requirements for biological activity of the marine alkaloid ascididemin

Lindsay BS, Barrows LR, Copp BR
Bioorg Med Chem Lett (1995) 5 : 739 -742
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.52	6.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL340160	ASCIDIDEMIN	—	1	6.52

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL340160	ASCIDIDEMIN	IC50	=	300.0	nM	6.52