Assay Detail
Binding
CHEMBL715754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of matrix metalloprotease-3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.09 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4524116 | — | — | 1 | 8.38 |
| CHEMBL111856 | — | — | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4524116 | — | IC50 | = | 4.2 | nM | 8.38 |
| CHEMBL111856 | — | IC50 | = | 16.0 | nM | 7.80 |