Assay Detail
Binding
CHEMBL715756
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Inhibition of Matrix Metalloprotease-3 (MMP-3)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.12 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL116756 | — | — | 1 | 7.82 |
| CHEMBL38851 | — | — | 1 | 7.60 |
| CHEMBL115623 | — | — | 1 | 7.21 |
| CHEMBL118740 | — | — | 1 | 6.51 |
| CHEMBL115467 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL116756 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL38851 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL115623 | — | IC50 | = | 62.0 | nM | 7.21 |
| CHEMBL118740 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL115467 | — | IC50 | = | 340.0 | nM | 6.47 |