Assay Detail
Binding
CHEMBL716484
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Effective concentration required for the biological activity against human Melanocortin 1 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Melanocyte-stimulating hormone receptor (CHEMBL3795) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Peptide science: exploring the use of chemical principles and interdisciplinary collaboration for understanding life processes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 10.35 | 10.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441738 | AFAMELANOTIDE | 4.0 | 1 | 10.64 |
| CHEMBL2096742 | — | — | 1 | 10.44 |
| CHEMBL440801 | — | — | 1 | 10.26 |
| CHEMBL214332 | INTERMEDINE | 2.0 | 1 | 10.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441738 | AFAMELANOTIDE | EC50 | = | 0.023 | nM | 10.64 |
| CHEMBL2096742 | — | EC50 | = | 0.036 | nM | 10.44 |
| CHEMBL440801 | — | EC50 | = | 0.055 | nM | 10.26 |
| CHEMBL214332 | INTERMEDINE | EC50 | = | 0.091 | nM | 10.04 |