Assay Detail
Binding
CHEMBL717005
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Inhibition of Matrix metalloprotease-13
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.43 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70176 | — | — | 1 | 8.10 |
| CHEMBL421699 | — | — | 1 | 7.33 |
| CHEMBL311509 | — | — | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70176 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL421699 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL311509 | — | IC50 | = | 138.0 | nM | 6.86 |