Assay Detail
Binding
CHEMBL717022
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Inhibition of Matrix metalloprotease-13
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.47 | 6.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL81113 | — | — | 1 | 6.63 |
| CHEMBL1169492 | — | — | 1 | 6.54 |
| CHEMBL82487 | — | — | 1 | 6.54 |
| CHEMBL78826 | — | — | 1 | 6.37 |
| CHEMBL308305 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL81113 | — | IC50 | = | 233.0 | nM | 6.63 |
| CHEMBL1169492 | — | IC50 | = | 291.0 | nM | 6.54 |
| CHEMBL82487 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL78826 | — | IC50 | = | 427.0 | nM | 6.37 |
| CHEMBL308305 | — | IC50 | = | 555.0 | nM | 6.26 |