Assay Detail
Functional
CHEMBL717402
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Inhibitory concentration against human cytomegalovirus (HCMV1) in MRC5 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.12 | 4.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119540 | — | — | 1 | 4.12 |
| CHEMBL332188 | — | — | 1 | - |
| CHEMBL119172 | — | — | 1 | - |
| CHEMBL326406 | — | — | 1 | - |
| CHEMBL119163 | — | — | 1 | - |
| CHEMBL442207 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119540 | — | IC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL332188 | — | IC50 | >> | 100000.0 | nM | - |
| CHEMBL119172 | — | IC50 | >> | 100000.0 | nM | - |
| CHEMBL326406 | — | IC50 | >> | 100000.0 | nM | - |
| CHEMBL119163 | — | IC50 | >> | 100000.0 | nM | - |
| CHEMBL442207 | — | IC50 | >> | 100000.0 | nM | - |