Assay Detail
Functional
CHEMBL717665
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity against mouse melanocortin-1 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Melanocyte-stimulating hormone receptor (CHEMBL4077) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Novel agouti-related-protein-based melanocortin-1 receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.07 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL407346 | — | — | 1 | 5.29 |
| CHEMBL2370694 | — | — | 1 | 5.23 |
| CHEMBL2370695 | — | — | 1 | 5.22 |
| CHEMBL2370696 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL407346 | — | EC50 | = | 5120.0 | nM | 5.29 |
| CHEMBL2370694 | — | EC50 | = | 5920.0 | nM | 5.23 |
| CHEMBL2370695 | — | EC50 | = | 5960.0 | nM | 5.22 |
| CHEMBL2370696 | — | EC50 | = | 28100.0 | nM | 4.55 |