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Assay Detail

CHEMBL718220

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Partial agonist potency against cloned Metabotropic glutamate receptor 2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 2 (CHEMBL5137)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Ligands for glutamate receptors: design and therapeutic prospects.
Bräuner-Osborne H, Egebjerg J, Nielsen EO, Madsen U, Krogsgaard-Larsen P.
J Med Chem (2000) 43 : 2609 -2645
PubMed 10893301 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.26 4.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2021372 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2021372 Ki = 55000.0 nM 4.26