Assay Detail
Binding
CHEMBL718941
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Inhibition of matrix metalloprotease-2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.20 | 9.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4524116 | — | — | 1 | 9.59 |
| CHEMBL111856 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4524116 | — | IC50 | = | 0.26 | nM | 9.59 |
| CHEMBL111856 | — | IC50 | = | 1.6 | nM | 8.80 |