Assay Detail
Functional
CHEMBL728518
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Tested for cytotoxicity in Molt-4 cells by XTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-4 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.77 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL133575 | — | — | 1 | 5.35 |
| CHEMBL336955 | — | — | 1 | 5.21 |
| CHEMBL341394 | — | — | 1 | 4.82 |
| CHEMBL334946 | — | — | 1 | 4.75 |
| CHEMBL293498 | — | — | 1 | 4.72 |
| CHEMBL422798 | — | — | 1 | 4.60 |
| CHEMBL132692 | — | — | 1 | 4.48 |
| CHEMBL337029 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL133575 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL336955 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL341394 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL334946 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL293498 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL422798 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL132692 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL337029 | — | IC50 | = | 55000.0 | nM | 4.26 |