Assay Detail
Binding
CHEMBL729176
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Affinity for recombinant Mineralocorticoid receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New steroidal diazo ketones as potential photoaffinity labeling reagents for the mineralocorticoid receptor: synthesis and biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 8.49 | 9.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103 | PROGESTERONE | 4.0 | 1 | 9.41 |
| CHEMBL97531 | — | — | 1 | 9.13 |
| CHEMBL2112398 | — | — | 1 | 7.70 |
| CHEMBL2112397 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103 | PROGESTERONE | Kd | = | 0.39 | nM | 9.41 |
| CHEMBL97531 | — | Kd | = | 0.74 | nM | 9.13 |
| CHEMBL2112398 | — | Kd | = | 20.0 | nM | 7.70 |
| CHEMBL2112397 | — | Kd | = | 20.0 | nM | 7.70 |