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Assay Detail

CHEMBL729495

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibitory activity against Monoamine oxidase in baboon brain was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Papio hamadryas
Tissue Brain
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Monoamine oxidase (CHEMBL2095205)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain.
Plenevaux A, Dewey SL, Fowler JS, Guillaume M, Wolf AP.
J Med Chem (1990) 33 : 2015 -2019
PubMed 2113950 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.38 7.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL58177 1 7.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL58177 IC50 = 41.7 nM 7.38