Assay Detail
Binding
CHEMBL731137
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Inhibitory activity against Monoamine oxidase from Bovine brain mitochondria
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Subcellular | Mitochondria |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.22 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121432 | — | — | 1 | 7.30 |
| CHEMBL331650 | — | — | 1 | 7.10 |
| CHEMBL120717 | — | — | 1 | 5.26 |
| CHEMBL332286 | — | — | 1 | 5.22 |
| CHEMBL331960 | — | — | 1 | - |
| CHEMBL331009 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121432 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL331650 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL120717 | — | Ki | = | 5500.0 | nM | 5.26 |
| CHEMBL332286 | — | Ki | = | 6000.0 | nM | 5.22 |
| CHEMBL331960 | — | Ki | = | 200000.0 | nM | - |
| CHEMBL331009 | — | Ki | = | 300000.0 | nM | - |