Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL732537

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibiting activity of the compound was determined against human Monoamine oxidase B
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
Manna F, Chimenti F, Bolasco A, Secci D, Bizzarri B, Befani O, Turini P, Mondovi B, Alcaro S, Tafi A.
Bioorg Med Chem Lett (2002) 12 : 3629 -3633
PubMed 12443791 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.47 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL331650 1 7.52
CHEMBL121432 1 7.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL331650 Ki = 30.0 nM 7.52
CHEMBL121432 Ki = 38.0 nM 7.42