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Assay Detail

CHEMBL734011

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Binding
Inhibitory concentration towards in human monoamine oxidase A was measured
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL1951)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.
Hubálek F, Binda C, Li M, Herzig Y, Sterling J, Youdim MB, Mattevi A, Edmondson DE.
J Med Chem (2004) 47 : 1760 -1766
PubMed 15027867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.46 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL887 RASAGILINE 4.0 1 6.16
CHEMBL1235738 AZILECT 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL887 RASAGILINE IC50 = 700.0 nM 6.16
CHEMBL1235738 AZILECT IC50 = 17700.0 nM 4.75