Assay Detail
Binding
CHEMBL734178
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Inhibitory concentration against Monoamine oxidase B was measured
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Papio hamadryas |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Rational approaches towards reversible inhibition of type B monoamine oxidase. Design and evaluation of a novel 5H-Indeno[1,2-c]pyridazin-5-one derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.15 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414637 | — | — | 1 | 9.50 |
| CHEMBL161907 | — | — | 1 | 8.05 |
| CHEMBL341071 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414637 | — | IC50 | = | 0.318 | nM | 9.50 |
| CHEMBL161907 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL341071 | — | IC50 | = | 130.0 | nM | 6.89 |