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Assay Detail

CHEMBL734671

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Dissociation Constant for human monoclonal antibody 2E2 with [3H]cocaine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 3 — Cell-line / Tissue
Curated By Expert

Target

Monoclonal antibody (mAb) 2E2 (CHEMBL612442)
Type UNKNOWN
Organism Homo sapiens

Publication

Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody.
Paula S, Tabet MR, Farr CD, Norman AB, Ball WJ.
J Med Chem (2004) 47 : 133 -142
PubMed 14695827 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.36 8.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL370805 COCAINE 4.0 1 8.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL370805 COCAINE Kd = 4.4 nM 8.36