Assay Detail
Functional
CHEMBL736575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its antagonistic activity against Moloney leukemia virus (MoLV) replication
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Moloney murine leukemia virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Moloney murine leukemia virus (CHEMBL613500) ↗| Type | ORGANISM |
| Organism | Moloney murine leukemia virus |
Publication
Synthesis and biological activity of sulfoximine-modified myristic acid analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.06 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45627 | CERULENIN | — | 1 | 5.57 |
| CHEMBL1627198 | — | — | 1 | 5.30 |
| CHEMBL1627197 | — | — | 1 | 5.00 |
| CHEMBL1627268 | — | — | 1 | 4.82 |
| CHEMBL1627196 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45627 | CERULENIN | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL1627198 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1627197 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1627268 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1627196 | — | IC50 | = | 24000.0 | nM | 4.62 |