Assay Detail
Binding
CHEMBL737061
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Mitogen-activated protein kinase p38 beta
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Pyrroles and other heterocycles as inhibitors of p38 kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.73 | 8.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL88486 | — | — | 1 | 8.09 |
| CHEMBL316275 | — | — | 1 | 8.00 |
| CHEMBL10 | SB-203580 | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL88486 | — | IC50 | = | 8.1 | nM | 8.09 |
| CHEMBL316275 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL10 | SB-203580 | IC50 | = | 78.0 | nM | 7.11 |