Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL744121

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the competitive inhibition against mouse brain N-Myristoyltransferase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Brain
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

S-(2-oxopentadecyl)-CoA, a nonhydrolyzable analogue of myristoyl-CoA, is a potent inhibitor of myristoyl-CoA:protein N-myristoyltransferase.
Paige LA, Zheng GQ, DeFrees SA, Cassady JM, Geahlen RL.
J Med Chem (1989) 32 : 1665 -1667
PubMed 2754690 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.62 7.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL448516 1 7.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL448516 Ki = 24.0 nM 7.62