Assay Detail
Functional
CHEMBL744192
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Agonistic activity in human OVCAR-3 (ovarian cancer cells)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OVCAR-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.69 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL153043 | — | — | 1 | 8.05 |
| CHEMBL357053 | — | — | 1 | 7.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL153043 | — | EC50 | = | 9.0 | nM | 8.05 |
| CHEMBL357053 | — | EC50 | = | 46.5 | nM | 7.33 |