Assay Detail
Binding
CHEMBL744934
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Compound was evaluated for binding affinity towards neurokinin NK1 receptor.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Morphan based substance P antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.30 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441225 | CP-99994 | — | 1 | 9.40 |
| CHEMBL2114439 | — | — | 1 | 9.20 |
| CHEMBL2115371 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441225 | CP-99994 | Ki | = | 0.3981 | nM | 9.40 |
| CHEMBL2114439 | — | Ki | = | 0.631 | nM | 9.20 |
| CHEMBL2115371 | — | Ki | < | 3162.28 | nM | - |