Assay Detail
Functional
CHEMBL748129
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the growth inhibition of OVCAR-3 ovarian tumor cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OVCAR-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.92 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7063 | — | — | 1 | 5.01 |
| CHEMBL7375 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7063 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL7375 | — | IC50 | = | 15000.0 | nM | 4.82 |