Assay Detail
Functional
CHEMBL748535
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against NCI-H358 cell line using MTT assay(mutant p53)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H226 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.02 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41701 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41701 | — | IC50 | = | 9500.0 | nM | 5.02 |