Assay Detail
Binding
CHEMBL748880
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Concentration required for 50% inhibition of influenza neuraminidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | unidentified influenza virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
C3-Thia and C3-carba isosteres of a carbocyclic influenza neuraminidase inhibitor, (3R,4R,5S)-4-acetamido-5-amino-3-propoxyl-1-cyclohexene-1-carboxylic acid
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.78 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54758 | — | — | 1 | 6.89 |
| CHEMBL55119 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54758 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL55119 | — | IC50 | = | 220.0 | nM | 6.66 |