Assay Detail
Binding
CHEMBL748883
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Concentration required for the inhibition of influenza neuraminidase activity by 50%
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | unidentified influenza virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and activity of C2-substituted analogs of influenza neuraminidase inhibitor GS 4071
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.37 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | -1.0 | 1 | 8.85 |
| CHEMBL53336 | — | — | 1 | 5.64 |
| CHEMBL57336 | — | — | 1 | 5.51 |
| CHEMBL52723 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL53336 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL57336 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL52723 | — | IC50 | = | 3400.0 | nM | 5.47 |