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Assay Detail

CHEMBL749047

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against rabbit muscle glycogen phosphorylase a in the absence of AMP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Tissue Muscle tissue
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glycogen phosphorylase, muscle form (CHEMBL3526)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
Kristiansen M, Andersen B, Iversen LF, Westergaard N.
J Med Chem (2004) 47 : 3537 -3545
PubMed 15214781 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL324288 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL324288 Ki = 11.0 nM 7.96