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Assay Detail

CHEMBL749485

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Evaluated for its antagonistic activity against the NT-stimulated cyclic [3H]GMP formation in murine N1E-115 neuroblastoma cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type N1E-115
Confidence 1 — Organism
Curated By Intermediate

Target

N1E-115 (CHEMBL612553)
Type CELL-LINE
Organism Mus musculus

Publication

UK-73,093: A non-peptide neurotensin receptor antagonist
Snider R, Pereira DA, Longo KP, Davidson RE, Vinick FJ, Laitinen K, Genc-Sehitoglu E, Crawley JN
Bioorg Med Chem Lett (1992) 2 : 1535 -1540
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.36 5.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38243 1 5.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38243 Ki = 4400.0 nM 5.36